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the gold nanoparticles (Au-NPs) they certainly have good potential, by virtue of their low cytotoxicity, their ability to withstand surface modifications induced by thiol-containing molecules, to immobilise a wide range of biomolecules (amino acids, enzymes, DNA) and for their high optical extinction coefficient.
Introduction Nanoparticles are, by definition, three-dimensional particles of nanometre (0-100 nm) size. In the field of ophthalmology, interest in them relates to the ability of some of them to......
LeggiA new indication for local steroid therapy
Dry eye is among the most frequent pathological conditions in ophthalmology. Up to 20% of adults over the age of 40 have dry eye symptoms. The origin of this......
LeggiRetinitis Pigmentosa is a rare hereditary disease that results in progressive vision loss.
About 15,000 people in Italy suffer from Retinitis Pigmentosa. The disease takes a different course depending on the case, manifesting itself at different ages but with increasingly disabling effects on life......
LeggiThe production and turnover of an efficient tear film is an essential condition for ocular surface health.
The eye is coated on the outside with a thin layer of tears, called the tear film, which is the complex end product of the activity of structures belonging to a functional unit known as the ocular surface.......
LeggiHyaluronic acid is a high molecular weight polyanionic polysaccharide with a typical spiral structure that gives it a particular ability to combine with water1 and excellent viscoelasticity. A ciò......
LeggiCarotid-cavernous fistulas (FCC) are abnormal communications between the carotids or branches thereof and the cavernous sinus (1,2). Although they represent a pathology of strict neuroradiological and neurosurgical relevance, they often......
LeggiAge-related macular degeneration (AMD) is the leading cause of severely reduced visual acuity in people over 60 in the western world. It is a complex disease that recognises several risk factors such as age, gender, race, light exposure, diet, cigarette smoking and vascular disease.
Recently, other elements seem to play an important role in the pathogenesis of the disease: variations in DNA sequences coding for complement factors, modifications of TMP-3 and activation of cytokines......
LeggiRead the interview with Prof. Michael A. Lemp.
Introduction (Read original article in English) Dry eye research has been very active over the last few decades and, in particular, its pace has accelerated......
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