- Sphingolipids are associated with numerous eye diseases, such as age-related macular degeneration, diabetic retinopathy and various eye diseases of autoimmune origin. Sphingolipids are a particularly abundant category of lipids within the plasma membrane and play a crucial role in promoting inflammation associated with ocular disorders. Understanding the mechanisms that regulate the inflammatory processes responsible for these disorders may lead to the design of more effective preventive strategies and treatments. Mondal K. et al. Role of Bioactive Sphingolipids in Inflammation and Eye Diseases. Adv Exp Med Biol., 2019. 1161:149-167
- Eye drops based on autologous plasma, i.e. from the same patient, prove to be effective and safe in the treatment of dry eye syndrome (Dry Eye Disease) and persistent corneal epithelial defects. A report recently published by the AAO (American Academy of Ophthalmology) summarised the results of decades of use of these products in clinical practice, pointing out, however, that the high cost of their production limits their use to only the most severe cases, in which other commercially available pharmacological options have failed. Shtein R.M. et al. Autologous Serum-Based Eye Drops for Treatment of Ocular Surface Disease: A Report by the American Academy of Ophthalmology. Ophthalmology.,2019. PMID:31561880
Dr. Carmelo Chines
Direttore responsabile
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